Table 4.
MCI participants in replication cohort (n = 49).
| Replication MCI cohort | p (vs. ADNI MCI) | |
|---|---|---|
| Male (%) | 26 (65%) | 0.183 |
| Age, mean (SD) | 69.3 (7.9) | <0.0001 |
| Education, mean (SD) | 16.5 (2.5) | 0.126 |
| Race | <0.0001 | |
| Asian (%) | 0 | |
| Black/African American (%) | 14 (29%) | |
| White (%) | 35 (71%) | |
| Non-Hispanic (%) | 49 (100%) | 0.578 |
| Having at least one APOE ε4 allele (%) | 14/28 (50%) | 0.684 |
| CSF biomarkers | ||
| Aβ42, mean (SD) in pg/mL | 179.7 (142.9) | 0.451 |
| t-Tau, mean (SD) in pg/mL | 62.5 (36.6) | <0.0001a |
| p-Tau181, mean (SD) in pg/mL | 29.6 (17.3) | 0.0001a |
| t-Tau/Aβ42 ≥ 0.39 (%) | 27 (55%) | 0.088 |
| sTNFR1 | 645.5 (179.4) | <0.0001a |
aLog10-transformed values were analyzed.