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. 2021 Jun 28;11:13378. doi: 10.1038/s41598-021-92677-z

Table 3.

Saliva-dry-LAMP clinical samples compared to reference RT-PCR methods (E gene and N2 gene) for saliva.

Saliva-Dry LAMP (S + RdRP) RT-PCR on Saliva RNA extracts (E and N2 gene) Total
Positive Negative
Positive 28 0 28
Negative 2 33 35
Total 30 33 63
PPA 93.33% (95% CI 77.93–99.18%)
NPA 100.00% (95% CI 89.42–100.00%)

Saliva-dry-LAMP was performed using commercially-available instruments and lyophilized RT-LAMP reactions from Pro-Lab Diagnostics Inc.

PPA positive percent agreement, NPA negative percent agreement, S spike, RdRP RNA-dependent RNA polymerase.