Table 2 –
Association of Risk Factors with Retinopathy of Prematurity
| Retinopathy of Prematurity | Fundus Pigmentation N (%)# | Lower Gestational Agec N (%) | Lower Birth Weightd N (%) | Tunica Vasculosa Lentis N (%) | Birth Status N (%) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Light | Medium/Dark | > 27 weeks | ≤ 27 weeks | >750 grams | ≤750 grams | Yes | No | Multiparous | Singleton | |
| Yes | 162 | 198 | 86 | 274 | 162 | 198 | 18 | 288 | 67 | 293 |
| 360 | (45%) | (55%) | (24%) | (76%) | (45%) | (55%) | (5%) | (80%) | (19%) | (81%) |
| No | 334 | 565 | 790 | 109 | 857 | 42 | 72 | 881 | 217 | 682 |
| 899 | (37%) | (63%) | (88%) | (12%) | (95%) | (5%) | (8%) | (98%) | (24%) | (76%) |
| Total | 496 | 763 | 876 | 383 | 1019 | 240 | 90 | 1169 | 284 | 975 |
| 1259 | (39%) | (61%) | (70%) | (30%) | (81%) | (19%) | (7%) | (93%) | (23%) | (77%) |
| Odds of ROP (OR [95% CI] p-value) | 1.38 [1.08–1.77] p = 0.01 | 23.1 [16.9–31.6] p <0.001 | 24.9 [17.2–36.2] p < 0.001 | 12.2 [7.2–20.9] p < 0.001 | 0.72 [0.53–0.98] p = 0.035 | |||||
All analyses performed with univariable logistic regression,
c
comparison of greater than to less than 27 weeks,
d
comparison of greater than to less than 750 grams,
#
percentages expressed respective to ROP groups;
Abbreviations: ROP = retinopathy of prematurity, OR = odds ratio, CI = confidence interval