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Toxicities to DA-R-EPOCH regimen in this study as compared to the prospective study by Duleavy et al. (6)
| Toxicities (Grade 3/4) | Dunleavy et al6 (n = 51) | Present Study (n = 37) |
|---|---|---|
| Hospitalization for FN | 13% of cycles |
23% of cycles (23/219) 14 (37.8%) patients |
| Anemia | Not reported | 9 (24.3%) |
| Peripheral Neuropathy | 8 (15.7%) | 7 (18.9%) |
| Mucositis | 4 (7.8%) | 4 (10.8%) |
| Ileus | 0 | 1 (2.7%) |
| Left ventricular dysfunction | 0 | 1 (2.7%) |
| AML | 1 (1.9%) | 0 |
