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. 2021 Jun 15;12:670753. doi: 10.3389/fphys.2021.670753

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Copyright © 2021 Vázquez-Mosquera, Fernández-Moreno, Cortés-Pereira, Relaño, Dalmao-Fernández, Ramos-Louro, Durán Sotuela, Rego-Pérez and Blanco.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evaluation of energy balance. (A) Total ATP production rate estimated from the values of oxygen consumption (OCR) and the proton production rate (PPR). The production rate of total ATP in pmol/min and the distribution of the rate corresponding to the production by OXPHOS (stripes) and by the glycolytic pathway (white) is represented. Significant differences (p < 0.05) are represented by continuous line (OXPHOS) and discontinuous line (glycolytic pathway). (B) Measurement of ATP production by luminescence, including both total and mitochondrial ATP. All data were obtained from three independent experiments, expressed as mean ratio in relation to BC ± deviation standard. *p < 0.05. BC = basal condition; PA = palmitic acid; OL = oleic acid; OXPHOS = oxidative phosphorylation.