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. 2021 Jun 24;16:4251–4276. doi: 10.2147/IJN.S301597

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© 2021 Salem et al.

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Right side of face before (A) and after topical tretinoin (B). Left side of the face before (C) and after ethosomal RP hydrogel (D). Peeling and dryness noted after topical tretinoin.