Table 4.
Ex vivo Permeation Parameters of Ethosomal RP Formulations
| Formulation | Lag Time (min) | Jss (µg/cm2 h) | Kp (cm/h) | EI |
|---|---|---|---|---|
| F1 | 25.4961 | 19.21 | 0.01921 | 1.24 |
| F2 | 39.60187 | 25.62 | 0.02562 | 1.66 |
| F3 | 25.13599 | 22.87 | 0.02287 | 1.48 |
| F4 | 56.02113 | 17.04 | 0.01704 | 1.1 |
| F5 | 15.37897 | 24.54 | 0.02454 | 1.59 |
| F6 | 16.5859 | 21.13 | 0.02113 | 1.37 |
| F7 | 35.55245 | 21.45 | 0.02145 | 1.39 |
| F8 | 55.94397 | 16.42 | 0.01642 | 1.06 |
| F9 | 25.40839 | 27.18 | 0.02718 | 1.76 |
| F10 | 52.13483 | 24.03 | 0.02403 | 1.56 |
| F11 | 62.58813 | 21.56 | 0.02156 | 1.4 |
| F12 | 44.97833 | 20.77 | 0.02077 | 1.34 |
| F13 | 36.67233 | 17.67 | 0.01767 | 1.14 |
| F14 | 22.37778 | 21.6 | 0.0216 | 1.4 |
| F15 | 51.42857 | 18.97 | 0.01897 | 1.23 |
| RP suspension | 73.12621 | 15.45 | 0.01545 | – |