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. 2021 Jun 15;11:685515. doi: 10.3389/fonc.2021.685515

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Copyright © 2021 Yi, Zhang, Ng, Xi, Ye, Cen, Li, Fan, Li, Hu, Rong, Xie, Zhao, Chen, Chen, Ni, Mi, Dai and Liao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Associations between TMGs and DEmiRNAs in RCC (A) and LCC (B). (C) The number of immune-related BPs in target genes of DEmiRNAs regulated by TMGs in RCC and LCC. (D) Venn diagrams show the overlap between the targets of TMG-downregulating DEmiRNAs and the targets of TMG-upregulating DEmiRNAs in RCC. The bar plots show the GO functional enrichment analysis of the corresponding parts of genes in the Venn diagram and the immune-related BPs are marked in red. (E) The crosslinks among TMGs, DEmiRNAs, and immune-related BPs in RCC and LCC. The red line represents positive relationships while the green line represents negative relationships.