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. 2021 Jun 15;12:663449. doi: 10.3389/fgene.2021.663449

TABLE 1.

Baseline characteristics of 328,850 participants according to sleep quality.

Characteristics (%) Sleep quality
Poor (n = 13,432) Less-healthy (n = 189,371) Healthy (n = 126,047)
Terminated health span 2,535 (18.87) 29,834 (15.75) 17,403 (13.81)
Age, years, mean (SD) 55.32 (7.89) 55.91 (7.99) 55.35 (8.27)
Townsend Index, mean (SD) −0.91 (3.26) −1.41 (3.03) −1.64 (2.89)
BMI, kg/m2, mean (SD) 29.22 (5.25) 27.50 (4.65) 26.38 (4.23)
Sex, female 6,359 (47.34) 1103,036 (54.41) 73,680 (58.45)
Ethnicity, white race 112,381 (92.18) 1179,379 (94.72) 1119,806 (95.05)
College or university degree 3,746 (27.89) 61,111 (32.27) 47,514 (37.70)
Smoking status
Current smokers 2,320 (17.27) 21,568 (11.39) 9,397 (7.46)
Never smokers 6,077 (45.24) 1101,789 (53.75) 77,450 (61.45)
Alcohol intake frequency
>3 times/week 5,915 (44.04) 87,335 (46.12) 55,260 (43.84)
Special occasions only/Never 2,665 (19.84) 32,431 (17.13) 22,404 (17.77)
Physical activity
Low 2,841 (21.15) 30,115 (15.90) 15,907 (12.62)
High 3,754 (27.95) 61,972 (32.73) 47,442 (37.64)
Healthy diet 8,825 (65.70) 1140,048 (73.95) 99,760 (79.15)
Family history of CCVD 8,615 (64.14) 1119,497 (63.10) 77,184 (61.23)
Family history of cancer 4,909 (36.55) 66,667 (35.20) 42,323 (33.58)
Sleep-related drugs use 227 (1.69) 1,565 (0.83) 404 (0.32)
Aspirin/ibuprofen use 3,826 (28.48) 46,494 (24.55) 26,286 (20.85)
Having low-risk sleep factors (%)
Early chronotype 879 (6.54) 93,740 (49.50) 1111,806 (88.70)
Sleep 7–8 h/day 548 (4.08) 1107,747 (56.90) 1119,576 (94.87)
Never/rarely insomnia 143 (1.06) 22,324 (11.79) 60,545 (48.03)
No self-reported snoring 612 (4.56) 96,133 (50.76) 1111,032 (88.09)
No frequent daytime sleepiness 10,639 (79.21) 1184,742 (97.56) 1125,777 (99.79)

The chi-square test for categorical variables and Kruskal–Wallis test for continuous variables were used to calculate the p values across the sleep quality, and all the variables had p value < 0.001. SD, standard deviation; BMI, body mass index; CCVD, cardiac–cerebrovascular disease.