Table 1.
Major features of genetic elements characterized in this work.
| Group | Genetic element | Accession number | Presence (+)or absence (−) of bla NDM | Chromosomal nucleotide position | Length(bp) | Host bacterium | Reference |
|---|---|---|---|---|---|---|---|
| Novel IME | Tn6588 | CP042860 | + | 4048158.4148181 | 100,024 | Providencia rettgeri 1701091 | This study |
| Tn6523-related IMEs | Tn6523 | AF261825 | − | Not applicable | 42,451 | Salmonella enterica Typhimurium DT104 | (Boyd et al., 2000) |
| Tn6589 | CP042857 | + | 4033353.4127100 | 93,748 | Proteus mirabilis 1701092 | This study | |
| Tn6512-related ICEs | Tn6512 | AY090559 | − | Not applicable | 88,549 | Providencia rettgeri 107 | (Boltner et al., 2002) |
| Tn6575 | MH160822 | + | Not applicable | 146,895 | Proteus vulgaris BC22 | (Kong et al., 2020) | |
| Tn6576 | CP042858 | + | 4485620.5019721 | 534,102 | K. pneumoniae D23 | This study | |
| Tn6577 | CP042857 | − | 3239622.3377168 | 137,547 | Proteus mirabilis 1701092 | This study | |
| Tn7-related elements | Tn7 | KX117211 | − | Not applicable | 14,067 |
E. coli
3.5-R3 |
(Peters and Craig, 2001) |
| Tn6726 | AP018750 | + | 5052592.5228430 | 175,839 |
K. pneumoniae
KP64 |
(Sakamoto et al., 2018) | |
| 40.7-kb Tn7-related element | CP042861 | + | 31628.72403 | 40,776 | Providencia rettgeri 51003 | This study | |
| Tn6591-related IMEs | Tn6591 | AE014073 | − | 2598547.2614010 | 15,464 | Shigella flexneri 2457T | (Boyd et al., 2000) |
| Tn6590 | CP042861 | − | 2252695.2268315 | 15,621 | Providencia rettgeri 51003 | This study |
For each group, all the fully sequenced and non-redundant blaNDM-carrying genetic elements available in GenBank (last accessed 15 December 2019) are included.