Figure 2.

Nuclear magnetic resonance structures of Acan1 (purple), Nak1 (green), and ShK (red).A, the 20 lowest energy structures are represented in stick format. B, the lowest energy structures are in ribbon representation. C, comparison of the functional dyad found in Acan1 (purple) and ShK (red). The lysine and neighboring aromatic tyrosine/amphipathic leucine that make up the functional dyad are shown. Nak1 (green) does not possess the functional dyad. Cysteine residues are labeled, and conserved disulfide bond connections are in yellow. Structure images were produced in MOLMOL.