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. 2021 May 7;7(5):459–470. doi: 10.1002/cjp2.220

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© 2021 The Authors. The Journal of Pathology: Clinical Research published by The Pathological Society of Great Britain and Ireland & John Wiley & Sons, Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Representative histologic findings in cases of fatal pandemic influenza taken from archival specimens. (A,B) DAD (×100 magnification). (C) DAD, edema, and hemorrhage adjacent to an airway containing inflammatory mucus (×100 magnification). (D) Interstitial capillary inflammation (×200 magnification). (E) Reactive pneumocytes exhibiting nucleoli and cytoplasmic vacuoles, similar to those seen in seasonal influenza and COVID‐19 (×400 magnification). (F) Superimposed bacterial pneumonia (×100 magnification).