Table 4.

Variables associated with a vascular event in giant-cell arteritis in a Cox proportional hazard model.

Variables at diagnosis	Univariate HR (95% CI)	p	Multivariate HR (95% CI)	p-value
Arterial hypertension	1.68 (0.84–3.33)	0.14	1.32 (0.44-3.90)	0.62
Hypercholesterolemia	1.98 (0.96–4.09)	0.07	2.12 (0.65–6.94)	0.21
Diabetes mellitus	2.14 (0.92–4.95)	0.07	2.77 (0.86–8.96)	0.09
Aortic surgery	7.27 (2.94–17.97)	<0.0001	10.46 (1.41–77.80)	0.02
Stroke	7.76 (2.30–26.22)	0.001	22.32 (3.69–135.05)	<0.001
Upper limb ischemia	8.91 (2.61–30.44)	<0.0005	20.27 (2.05–200.12)	0.01
Lower limb ischemia	5.28 (1.24–22.52)	0.02	76.57 (2.89–2027.69)	0.009
Lower limbs arteritis stage II/III/IV	3.80 (1.70–8.48)	0.001	3.18 (0.85–11.91)	0.086
Atheroma at CT-scan	1.95 (0.91–4.18)	0.09	3.06 (1.06–8.82)	0.04
Aortic aneurysm	1.93 (0.82–4.57)	0.13	2.09 (0.48–9.01)	0.32
Aortic dissection	2.84 (0.67–12.08)	0.16	2.74 (0.22–34.69)	0.44
Aortitis of descending thoracic aorta	2.06 (0.95–4.44)	0.07	4.64 (1.56–13.75)	0.006
Aortitis of abdominal aorta	2.00 (0.92–4.34)	0.08	0.64 (0.20–2.03)	0.45
Statin at diagnosis	2.56 (1.20–5.46)	0.01	0.72 (0.13–4.08)	0.71
Antiplatelet drug at diagnosis	1.47 (0.71–3.08)	0.30	3.27 (0.84–12.70)	0.09

CI, confidence interval; CT, computed tomography; HR, hazard ratio. Bold p value are <0.05.