Figure 2. Intention-to-Treat Hazard Ratios (HRs) and Event Rate Reduction for All-Cause Mortality in the Overall Cohort and Prespecified Subgroups.
Hazard ratios of all-cause mortality in the overall cohort and by age category, cardiovascular disease (CVD) status, estimated glomerular filtration (eGFR) category, albuminuria category, body mass index (BMI) category (calculated as weight in kilograms divided by height in meters squared), and baseline use of metformin, insulin, angiotensin-converting enzyme inhibitors or angiotensin receptor blockers (ACE inhibitor/ARB), and diuretics. SGLT2 indicates sodium-glucose cotransporter-2.
aAlbuminuria status was categorized using albumin to creatinine ratio (ACR): no albuminuria (ACR ≤30 mg/g), microalbuminuria (ACR >30 to ≤300 mg/g), and macroalbuminuria (ACR >300 mg/g).