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. 2021 Jun 29;2021(6):CD004011. doi: 10.1002/14651858.CD004011.pub4

McDonald 1999.

Study characteristics
Methods Study design: RCT
Dates study conducted: November 1995‐October 1996
Participants Number of participants: eligible, unclear; 48 randomised; 48 reported
Country: Australia
Population: men
Inclusion criteria: patients undergoing TURP
Condition for hospitalisation: TURP
Exclusion criteria: not reported
Age (mean and range): A 66.7 (51‐81); B 68.7 (57‐89); overall: 67.8 (51‐89)
Use of antibiotic prophylaxis: not reported
Interventions Group A (n = 20): removal of IUC at midnight
Group B (n = 28): removal of IUC at 6 am
Size and type of catheter used: not reported
Study definition of short‐term catheterisation (days): not reported
Intended duration of catheterisation for each group:
A: IUC removed at midnight
B: IUC removed at 6 am
Outcomes Mean volume of first void
Mean time to first void
Discharged same day as IUC removal
Discharged next day
Definition of CAUTI or bacteriuria Not reported
Sponsorship/funding Not reported
Ethical approval “The study was approved by the research committee; verbal consent was judged adequate for participation in this investigation.”
Notes 3 participants were withdrawn from analysis as 1 passed urine in the toilet without informing the staff, the second experienced an extended length of stay due to superficial vein thrombosis and the third failed his trial of void for 10 h after catheter removal.
There was no significant difference between the 2 groups with respect to tissue pathology.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote: “A random‐digit chart was used to allocate patients”
Comment: method of randomisation unclear
Allocation concealment (selection bias) Unclear risk Not reported
Blinding of participants and personnel (performance bias)
All outcomes High risk Not reported. Unlikely participants were able to be blinded.
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk Not reported
Blinding of microbiological outcome (detection bias) Low risk No microbiological outcomes reported
Incomplete outcome data (attrition bias)
All outcomes Unclear risk 3/48 excluded from analysis. Unclear which group these 3 belonged to.
Selective reporting (reporting bias) Low risk All outcomes seem to be reported in full in both the methods and results section. Protocol not available.
Other bias Low risk Appears to be free from other sources of bias