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. 2021 Jun 29;2021(6):CD004011. doi: 10.1002/14651858.CD004011.pub4

Noble 1990.

Study characteristics
Methods Study design: quasi‐RCT
Dates study conducted: not reported
Participants Number of participants: 108 eligible; 108 randomised; 86 reported
Setting: London
Country: UK
Population: mixed
Age (mean and SD): not reported
Inclusion criteria: patients requiring urethral catheterisation that were admitted to the urology unit
Condition for hospitalisation: urological procedures and surgery
Exclusion criteria: patients who had UTI prior to recruitment
Use of antibiotic prophylaxis: not reported
Interventions Group A (n = 46): removal of IUC at 6 am
Group B (n = 40): removal of IUC at midnight
Size and type of catheter used: not reported
Study definition of short‐term catheterisation (days): not reported
Outcomes Volume of first void
Time to first void
Discharge same day as IUC removal
IUC not removed on time
Definition of CAUTI or bacteriuria Not reported
Sponsorship/funding Not reported
Ethical approval Not reported
Notes 22 participants excluded from study due to pre‐existing UTIs
More men than women in each group
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk Quote: “… entered alternately into 1 of 2 groups …”
Comment: quasi‐randomisation method
Allocation concealment (selection bias) High risk Quote: “… entered alternately ….”
Comment: unlikely any concealment occurred. Participant group could easily be found
Blinding of participants and personnel (performance bias)
All outcomes High risk Not reported. Not likely possible to blind participants
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk Not reported
Blinding of microbiological outcome (detection bias) Low risk No microbiological outcomes reported
Incomplete outcome data (attrition bias)
All outcomes Low risk No withdrawals, all data reported in full
Selective reporting (reporting bias) Low risk All outcomes seem to be reported in full in both methods and results
Other bias Low risk Appears to be free from other sources of bias