Table 1. Demographics and Baseline Characteristics.
| Characteristic | Standard of care | Home healtha |
|---|---|---|
| Age | ||
| Participants, No. | 19 | 23 |
| Mean (SD), y | 64.1 (10.0) | 65.0 (10.9) |
| Sex, No. (%) | ||
| Male | 11 (58) | 13 (57) |
| Female | 8 (42) | 10 (43) |
| Time since Parkinson disease diagnosis | ||
| Participants, No. | 19 | 23 |
| Mean (SD), y | 11.5 (7.2) | 12.0 (5.9) |
| Race, No. (%) | ||
| White | 19 (100) | 21 (91) |
| African American | 0 | 2 (9) |
| Ethnicity, No. (%) | ||
| Hispanic or Latino | 1 (5) | 3 (13) |
| Not Hispanic or Latino | 18 (95) | 20 (87) |
| Deep brain stimulation target, No. (%) | ||
| Subthalamic nucleus | 3 (16) | 5 (22) |
| Globus pallidus internus | 16 (84) | 18 (78) |
| No. of deep brain stimulation leads, No. (%) | ||
| Unilateral | 11 (58) | 12 (52) |
| Bilateral | 8 (42) | 11 (48) |
| Total UPDRS off-medication scoreb | ||
| Participants, No. | 18 | 23 |
| Mean (SD) | 46.8 (14.0) | 60.1 (20.3) |
| Off-levodopa/on-levodopa responsec | ||
| Participants, No. | 19 | 23 |
| Mean (SD), % | 31.0 (24.0) | 37.0 (21.0) |
| UPDRS III off-medication scorec | ||
| Participants, No. | 19 | 23 |
| Mean (SD) | 33.5 (9.4) | 40.5 (12.9) |
| UPDRS III on-medication scorec | ||
| Participants, No. | 19 | 23 |
| Mean (SD) | 23.2 (10.9) | 25.3 (11.9) |
| PDQ-39 score | ||
| Participants, No. | 18 | 23 |
| Mean (SD) | 21.2 (22.5) | 33.6 (21.2) |
| Levodopa equivalent daily dose, mg | ||
| Participants, No. | 11 | 14 |
| Mean (SD) | 1104.0 (579.7) | 1174.6 (612.7) |
| Caregivers enrolled, No. (%) | 14 (74) | 22 (96) |
| Multidimensional Caregiver Strain Index score | ||
| Participants, No. | 12 | 21 |
| Mean (SD) | 12.7 (13.8) | 16.1 (12.6) |
Abbreviations: PDQ-39, 39-question Parkinson’s Disease Questionnaire; UPDRS, Unified Parkinson’s Disease Rating Scale; UPDRS III, Unified Parkinson’s Disease Rating Scale part III.
a
Patients in the home health arm had slightly more parkinsonism, as indicated by the higher mean total UPDRS and UPDRS III off-medication scores.
b
The total UPDRS is the sum of parts I, II, III, and IV.
c
Preoperative baseline used.