Table 2.

clinical variables during treatment in two groups

Variable	T0	T24	T48	T72	T96
SOFA
Intervention	12.45 ± 2.65	10.27 ± 2.60	7.1 ± 1.92	3.72 ± 1.75	1.62 ± 1.19
Control	10.7 ± 2.70	8.8 ± 2.65	7.92 ± 2.81	4.85 ± 2.51	3.10 ± 1.61
P value	< 0.001	0.01	0.93	0.01	< 0.001
PCT
Intervention	37.25 ± 20.93	26.50 ± 15.30	11.10 ± 6.04	4.02 ± 2.34	1.36 ± 0.79
Control	45.28 ± 28.60	28.07 ± 17.48	16.27 ± 11.71	7.72 ± 7.29	2.82 ± 1.39
P value	0.15	0.67	0.01	< 0.001	< 0.001
CRP
Intervention	27.40 ± 11.66	36.60 ± 13.85	14.97 ± 7.31	6.70 ± 3.61	2.30 ± 0.66
Control	24.27 ± 12.83	45.1 ± 19.50	24.32 ± 12.72	11.47 ± 7.51	4.79 ± 1.78
P value	0.25	0.02	< 0.001	< 0.001	< 0.001
Pao2/Fio2
Intervention	116.42 ± 27.60	191.49 ± 25.60	224.62 ± 23.40	262.87 ± 30.59	292.65 ± 29.42
Control	160.51 ± 29.70	188.21 ± 26.61	208.50 ± 28.88	229.95 ± 33.10	257.20 ± 33.73
P value	0.99	0.6	< 0.001	< 0.001	< 0.001
Vitamin C
Intervention	20.63 ± 12.74				79.20 ± 26.42
Control	22.77 ± 13.56				16.38 ± 10.33
P value	0.47				< 0.001

SOFA Sequential organ failure assessment

PCT Procalcitonin (microgram per liter)

CRP C reactive protein (milligram per liter)

VIT C (milligram per liter)