Table 3.
Antioxidant enzymes and malondialdehyde levels of alloxan-induced diabetic rats orally administered chromatographic fractions of C. albidum stem bark.
Treatment Group | SOD (unit/mg protein) | Catalase (unit/mg protein) | Malondialdehyde (nmol/L) |
---|---|---|---|
Control | 4.924 ± 0.68a | 334.216 ± 37.02a | 2.062 ± 0.77a |
DR + 1 ml of DW | 0.764 ± 0.19b | 123.183 ± 25.08b | 3.763 ± 0.48b |
DR + 2.5 mg/kg b. wt of glibenclamide | 2.517 ± 0.36c | 194.885 ± 23.04c | 2.43 ± 0.55a |
DR + 2.5 mg/kg b. wt of F 5 | 2.761 ± 0.36c | 266.699 ± 41.22d | 1.96 ± 0.45a |
DR + 2.5 mg/kg b. wt of F7 | 4.395 ± 0.26a | 346.162 ± 82.08a | 2.03 ± 0.16a |
Values are means of ten replicates ± SEM.
Values with different superscripts are significantly different from each other (p < 0.05).
Where
Control = non-diabetic rats receiving 1 ml of distilled water; DC = diabetic rats receiving 1 ml of distilled water; RD = diabetic rats receiving standard drug; F5 = diabetic rats receiving chromatographic fraction 5; F7 = diabetic rats receiving chromatographic fraction 7