Table 4.
Serum Lipids of Alloxan-induced Diabetic Rats Orally Administered Ethyl Acetate Chromatographic Fractions of Chrysophyllum albidum Stem Bark for 14 days.
Treatment Group | Cholesterol | Triglyceride | HDL-C | LDL-C | VLDL-C | Atherogenic index (LDL-C/HDL-C) |
---|---|---|---|---|---|---|
Control | 26.12 ± 0.5d | 4.14 ± 0.5a | 16.69 ± 1.5d | 8.60 ± 1.6c | 0.83 ± 0.1a 0.83 ± 0.1a | 0.52 ± 0.1b |
DC | 57.92 ± 1.0e | 26.98 ± 0.9c | 3.55 ± 0.6a | 48.98 ± 1.2d | 5.40 ± 0.2c | 14.12 ± 2.5c |
RD | 11.04 ± 0.6a | 10.30 ± 0.3b | 7.28 ± 0.7b | 1.69 ± 0.2a | 2.06 ± 0.1b | 0.23 ± 0.0a |
F 5 | 15.65 ± 0.6b | 3.21 ± 0.45a | 11.41 ± 1.1c | 3.60 ± 0.55b | 0.64 ± 0.1a | 0.32 ± 0.1a |
F7 | 17.20 ± 0.8c | 3.95 ± 0.4a | 12.25 ± 1.3c | 4.16 ± 0.7b | 0.79 ± 0.1a | 0.35 ± 0.1a |
Values are means of ten replicates ± SEM.
Values with different superscripts are significantly different from each other (p < 0.05). Where: Control = non-diabetic rats receiving 1 ml of distilled water; DC = diabetic rats receiving 1 ml of distilled water; RD = diabetic rats receiving standard drug; F5 = diabetic rats receiving chromatographic fraction 5; F7 = diabetic rats receiving chromatographic fraction 7.