Table 3.
Summary of current-clamp properties of DRG cells.
| Loxp | KO | Loxp CFA | KO CFA | |
|---|---|---|---|---|
| Cm (pF) | 27.1 ± 1.6 (20) | 28.2 ± 1.8 (20) | 29.4 ± 1.8 (20) | 29.9 ± 1.6 (20) |
| Rin (MΩ) | 564.0 ± 48.4 (15) | 485.7 ± 47.8 (15) | 532.1 ± 47.1 (14) | 474.7 ± 47.7 (17) |
| RMP (mV) | −58.1 ± 0.7 (15) | −58.7 ± 0.6 (17) | −60.3 ± 0.5 (17) | −59.4 ± 0.9 (15) |
| AP amplitude (mV) | 107.4 ± 2.9 (16) | 107.6 ± 3.0 (17) | 105.2 ± 1.1 (16) | 107.8 ± 2.4 (20) |
| Current threshold (pA) | 132.1 ± 10.9 (20) | 265.7 ± 34.1 (20)** | 54.1 ± 8.2 (16) | 142.1 ± 12.4 (20)## |
The number of cells analyzed for each parameter is provided in parentheses.
**
indicates p < 0.01, compared to Loxp group.
##
indicates p < 0.01, compared to Loxp CFA group.