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Saffron and Crocin suppressed fibrosis and Collagenesis in adhesive tissues. (A, C) Masson’s trichrome staining showed a significant reduction of deposition of Collagen (asterix) in Crocin- or Saffron-treated rat in different groups (B) The decrease in collagen thickening was not significant in the case of oral administration of Saffron, compared to control. ∗∗∗p < 0.001.
