Skip to main content
. 2021 Jan 20;31:137–153. doi: 10.1016/j.jare.2021.01.007

Fig. 4.

Fig. 4

(a) IFNAR blocked-infected spleen was found shrunken at 7 dpi (n = 3). (b) Spleen showed marked enlargement and widespread edema at 15 dpi (n = 3). (c) Isotype-infected control spleen showed normal white and red pulp areas (n = 27). H&E, scale bar 200 µm. (d) Starry-sky pattern due to apoptosis of lymphocytes in white pulp at 7 dpi (n = 3). H&E, scale bar 100 µm. e. Spleen showed lymphoid depletion, golden brown hemosiderin pigments and neutrophilic infiltration at 7 dpi (n = 3). H&E, scale bar 100 µm. (f) IFNAR blocked-infected spleen showed hyperplasia of white pulp at 15 dpi (n = 3). H&E, scale bar 400 µm.