Table 3.
Aortic wall thickness and collagen content, and hepatic lipid accumulation.
Parameters | Control | HF | HF + dMF100 | HF + dMF300 |
---|---|---|---|---|
Aortic wall thickness (μm) | 275 ± 8 | 386 ± 11∗ | 314 ± 6 ∗,## | 338 ± 6∗,## |
Area of medial collagen (%) | 31.5 ± 1.3 | 48.9 ± 1.2∗ | 39.5 ± 1.6∗,## | 40.9 ± 1.4∗,## |
Proportion of hepatic lipid (%) | 33.6 ± 2.1 | 51.9 ± 1.2∗∗ | 43.0 ± 2.6∗, # | 42.0 ± 1.6∗, # |
Control, normal diet; HF, high-fat diet; HF + dMF100, high-fat diet+100 mg/kg dried mulberry fruit powder; HF + dMF300, high-fat diet+300 mg/kg dried mulberry fruit powder. Aortic wall thickness was measured as the perpendicular distance between the inner wall of the tunica intima to the outer extremity of the tunica media. Hepatic lipid was the area occupied by oil red O positive staining and expressed as the proportion of region of interest area. Values are means ± SEM (n = 5 mice). ∗P < 0.01, ∗∗P < 0.001 vs. Control. #P < 0.05, ##P < 0.01 vs. HF.