Table 4.
Binding of dMF or cholestyramine to bile acids (taurocholic acid and taurodeoxycholic acid) in vitro.
Concentrations of dMF or cholestyramine (mg/mL) | Bile acid binding |
|||
---|---|---|---|---|
Taurocholic acid |
Taurodeoxycholic acid |
|||
dMF (% of control) | Cholestyramine (% of control) | dMF (% of control) | Cholestyramine (% of control) | |
0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 |
0.1 | 0.0 ± 0.0 | 4.9 ± 11.3 | 0.0 ± 0.0 | 8.2 ± 13.8 |
1 | 0.0 ± 0.0 | 47.2 ± 3.0∗∗ | 0.0 ± 0.0 | 87.3 ± 3.7∗ |
5 | 0.0 ± 0.0 | 83.6 ± 2.1∗∗ | 0.0 ± 0.0 | 93.8 ± 2.1∗∗ |
10 | 16.6 ± 5.9## | 87.7 ± 1.7∗∗ | 10.2 ± 25.5# | 96.5 ± 2.6∗∗ |
dMF, dried mulberry fruit powder. Values are means ± SEM (n = 3).
∗P < 0.01, ∗∗P < 0.001 vs. control. #P < 0.01, ##P < 0.001 vs. cholestyramine at the same concentration.