Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 22;24(2):597. doi: 10.3892/mmr.2021.12236

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 3. — SNHG8 serves a protective role in HI/R myocardial injury by regulating miR-335. (A) The Cell Counting Kit-8 assay was used to examine cell viability in the different conditions. ***P<0.001 vs. HI/R. (B) Cell proliferation was determined by EdU analysis **P<0.01. (C) LDH assay was used to detect LDH release **P<0.01. (D) Flow cytometric analysis was used to determine cell apoptosis in the different groups *P<0.05. (E) The expression levels of Bax, Bcl-2 and cleaved caspase-3 were determined by western blotting. *P<0.05 vs. HI/R+ miR-335 inhibitor + NC siRNA. HI/R, hypoxia-ischemia-reoxygenation; LDH, lactate dehydrogenase; miR, microRNA; NC, negative control; siRNA, small interfering RNA; SNHG8, small nucleolar RNA host gene 8.