Table 1.
Demographics
| Demographics | non-COVID | COVID+ | p Value |
|---|---|---|---|
| Total participants | 22 | 22 | |
| Age, median (IQR) | 50 (39.5-56) | 50.5 (43-56.3) | 0.67 |
| Male, n (%) | 16 (72.7) | 16 (72.7) | 1 |
| Weight (kg), median (IQR) | 79.7 (70.8-106.6) | 99.6 (78.6-113.8) | 0.14 |
| BMI (kg/m2), median (IQR) | 28.7 (26.1-34.8) | 31.2 (29.1-37.9) | 0.087 |
| Comorbidities | |||
| Hypertension, n (%) | 7 (31.8) | 9 (40.9) | 0.75 |
| Diabetes mellitus, n (%) | 3 (13.6) | 5 (22.7) | 0.69 |
| Chronic kidney disease, n (%) | 2 (9.1) | 3 (13.6) | 1 |
| Coronary artery disease, n (%) | 1 (4.5) | 2 (9.1) | 1 |
| COPD, n (%) | 4 (18.2) | 0 (0) | 0.11 |
| Cause of ARDS | <0.001 | ||
| COVID-19, n (%) | 0 (0) | 22 (100) | |
| Influenza, n (%) | 9 (40.9) | 0 (0 | |
| Bacterial pneumonia, n (%) | 6 (27.3) | 0 (0) | |
| Other,* n (%) | 7 (31.8) | 0 (0) | |
| ECMO initiation year, (n, %) | |||
| 2019 | 13 (59.1) | 0 (0) | <0.001 |
| 2020 | 9 (40.9) | 22 (100) | |
| Venovenous configuration, n (%) | 22 (100) | 22 (100) | 1 |
| Femoral-IJ, n (%) | 19 (86.4) | 20 (90.9) | 0.60 |
| IJ dual-lumen cannula, n (%) | 1 (4.5) | 0 (0) | |
| Femoral-femoral, n (%) | 2 (9.1) | 2 (9.1) | |
| ECMO duration (h), median (IQR) | 480 (184-625) | 618 (306-990) | 0.19 |
| Survival to hospital discharge, n (%) | 15 (68.2) | 16 (72.7) | 1 |
| Tracheostomy on ECMO, n (%) | 12 (54.5) | 12 (54.5) | 1 |
NOTE. Continuous variables analyzed with Mann-Whitney U test. Categorical variables analyzed with Fisher exact test.
Abbreviations: ARDS, acute respiratory distress syndrome; BMI, body mass index; COPD, chronic obstructive pulmonary disease; COVID-19, coronavirus disease 2019; COVID+, COVID-positive; non-COVID, non-COVID related respiratory failure; ECMO, extracorporeal membrane oxygenation; IJ, internal jugular vein; IQR, interquartile range.
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Other includes transfusion-related acute lung injury, trauma, sepsis, pancreatitis, unknown.