Table 1.
The physicochemical properties of liposomes
Physicochemical properties | iRGD-liposome-ASO 1 | iRGD-liposome-ASO 2 | Liposome-ASO |
---|---|---|---|
Mean Sizes (nm) | 150 ± 36 | 210 ± 83 | 141 ± 36 |
PDI | 0.0838 | 0.0850 | 0.0863 |
Zeta (mV) | −6.67 ± 0.18 | −7.10 ± 0.42 | −14.4 ± 7.25 |
ASO Cone. (mg/mL) | 8.093 ± 0.674 | 7.434 ± 0.804 | 7.368 ± 0.951 |
Data are presented as the mean ± standard deviation (n=3).
Abbreviations: ASO, antisense oligonucleotide; PDI, polydispersity index; conc., concentration.