Fig. 7. Biodistribution of FNDs and HA–FND conjugates in five different organs at (a) 6 h and (b) 30 h after intravenous injection (n = 3). Error bars represent standard deviation of three experiments (*P ≤ 0.05 and **P ≤ 0.01, FNDs vs. HA–FND conjugates in the liver and lung). (c) The absorbance spectra of urine 48 h after intravenous injection of HA–FND conjugates. (d) Quantitative analysis of renal clearance after intravenous injection of FNDs and HA–FNDs (n = 3). (e) Histological analysis with H&E staining of dissected liver, heart, lung, kidney, and spleen after intravenous injection of HA–FND conjugates.
