Table 2.

Common types of image analysis software (courtesy of Joseph Johnson, Moffitt Cancer Center)

	Image format compatibility	Technical knowledge level	Customization level	Features
Basic science image analysis	Most image formats	Moderate	High	Variety of measurement tools
				Access to image processing tools
				Some automation
Slide scanner based	Limited image formats	Low	Lowmoderate	Direct access to images
				Access to common algorithms
				US IVD for HER2/ER available
				Pattern recognition
				Batch processing
				Designed for digital pathology
Digital pathology inspired	Most image formats	Moderate	Moderate	Workflow based
				Easily adjustableparameters
				Batch processing
				Pattern recognition
				Access more feature data
				Designed for digital pathology
Algorithm based	Most image formats	High	High	Fully customizable
				Unique algorithms
				Even more feature data
				Batch processing

IVD: In vitro diagnostics, ER: Estrogen receptor, HER2: Human epidermal growth factor receptor 2