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. 2021 Jul;21(7):1014–1026. doi: 10.1016/S1473-3099(20)30601-0

Table.

Summary of factors detectable within the first 4 days of illness and their association with progression to severe dengue disease

Associated with progression Not associated with progression
Demographics and comorbidity Older age (in adults), younger age (in children), female sex, diabetes, hypertension, renal disease, cardiovascular disease Nutritional status, bodyweight, mixed comorbidity
Signs and symptoms Vomiting, abdominal pain and tenderness, bleeding, and pleural effusion or ascites Rash, headache, and positive tourniquet test
Laboratory parameters Platelet count, aspartate aminotransferase, alanine aminotransferase, serum albumin, and secondary infection White blood cell count, haematocrit
Virological profile Dengue viral serotype 2 (in children) Viral load