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. 2021 May 26;40:e2020415. doi: 10.1590/1984-0462/2022/40/2020415

Table 2. Characteristics of studies related to MERS-CoV.

MERS-CoV Author/year Study population Study design and intervention Outcome measures Conclusions
Assiri et al., 2016 16 n=5 pregnant women. Case report Two patients died, two cases resulted in perinatal death, one pregnancy led to intrauterine fetal demise, and one infant died after an emergency cesarean section. MERS-CoV may pose serious health risks to both mothers and infants during pregnancy.
Alfaraj et al., 2019 17 n=2 pregnant women. Case report Both patients did not deliver during hospitalization and subsequently delivered a healthy infant at term. The outcome was favorable in most pregnancies associated with MERS-CoV cases.
Jeong et al., 2017 18 n=1 39-year-old pregnant woman. Case report Benign maternal course that resulted in full recovery with subsequent healthy full-term delivery. Further studies with a larger sample size will expand the knowledge of pathophysiology and perinatal outcome.
Alserehi et al., 2016 19 n=1 33-year-old pregnant woman. Case report Preterm delivery of a male infant without complications. The pregnancy had a favorable outcome for the newborn.
Malik et al., 2016 20 n=1 32-year-old woman. Case report Preterm delivery of a male infant without complications. The mother presented a progressive worsening of clinical status, leading to death. MERS-CoV infection and pregnancy were a fatal combination in this case.
Park et al., 2016 21 n=1 39-year-old woman. Case report Placental abruption; urgent C-section. The pregnancy had a favorable outcome for both mother and newborn.
Payne, 2014 22 n=1 39-year-old pregnant woman. Case report Second-trimester stillbirth in a pregnant woman with MERS-CoV infection. MERS-CoV infection during pregnancy may pose serious health risks to both mother and fetus.