Figure 1.

Representative images for immunohistochemistry (IHC) staining of serine hydroxymethyltransferase2 (SHMT2) in papillary thyroid carcinoma (PTC) tissue. Tissue without (0, (A) and (B)) or weak (1+, (C) and (D)) SHMT2 protein expression were classified as negative, and tissues with moderate (2+, (E) and (F)) or strong (3+, (G) and (H)) SHMT2 protein expression were classified as positive. (A), (C), (E), and (G) were low magnification images (×200) and (B), (D), (F), and (H) were high magnification images (×400).