Table 2.

Summary of data synthesis.

Clinical features	OR (95% CI)	P value	Heterogeneity		Pub bias
			Q test	I 2 (%)	Harbord test
Age	1.16 (0.82–1.64)	0.40	0.46	0	0.154
Sex	0.84 (0.56–1.26)	0.40	0.63	0	0.516
Size of primary lesion	1.18 (0.67–2.09)	0.57	0.04	59	0.541
Ipsilateral central lymph node metastasis	1.16 (0.83–1.62)	0.37	0.58	0	0.490
HT	1.57 (1.13–2.20)	0.008	0.24	28	0.333
Multifocality of primary lesion	3.93 (2.70–5.73)	<0.00001	0.87	0	0.025
Multifocality of contralateral lesion	1.32 (0.56–3.10)	0.52	0.04	68	0.220
Capsular invasion	1.61 (1.10–2.36)	0.01	0.38	2	0.115