Table 4.

Performance of multivariate predictive model of GDM including thyroid hormones and routine variables at a fixed false-positive rate of 10%.

Models	AUC (95% CI)	Sensitivity (%)	Specificity (%)	NPV (%)	PPV (%)	Cut-off	P
Model 1	0.703 (0.686,0.720)	26.5	90.0	89.7	27.1	0.208	0.060
Model 2	0.710 (0.693,0.729)	29.2	90.0	90.0	29.1	0.211	0.477
Model 3	0.726 (0.709,0.743)	30.8	90.0	90.2	30.1	0.215	0.072
Model 4	0.724 (0.707,0.741)	32.4	90.0	90.4	31.3	0.215	0.685

P value of Hosmer–Lemeshow good of fit test. Model 1 including maternal age, pre-pregnancy BMI, history of family diabetes, and season of conception; Model 2 based on model 1, plus fasting plasma glucose and sampling gestational week; Model 3 based on model 2, plus T3; Model 4 based on model 2, plus T3/fT4.

AUC, area under curve; NPV, negative predictive value; PPV, positive predictive value.