Figure 5.

The effect of acute atosiban treatment in gestating mice. (A) Non-gestating (NG) mice and gestating (G) mice at 2 weeks of gestation received vehicle or atosiban 30 min before glucose loading for the glucose tolerance test (GTT). Blood glucose levels were recorded. (B) The area under curve (AUC) of THE GTT in (A). *P < 0.05, ***P < 0.001 as indicated, n = 8. (C) Serum insulin concentrations were measured at different times before and after glucose loading during the GTT in (A). (D) The AUC of the first (1st) phase (0 to 10 min) of insulin secretion in (C). *P < 0.05, **P < 0.01 as indicated, n = 8. (E) The AUC of the second (2nd) phase (10 to 120 min) of insulin secretion in (C). *P < 0.05, ***P < 0.001 as indicated, n = 8.