Table 3. Relationship between interleukin-6 and the severity of acute coronary syndrome.
| Author (s) | Population (ethnicity) | Published time | Groups | Groups of cases | Severity degree | IL-6, pg/mL | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nishida et al. (13) | Japan | 2011 | STEMI/NSTEMI/UA | 41/40/40 | STEMI | NSTEMI | UA | STEMI | NSTEMI | UA | ||
| hs-CRP (mg/L) | 4.7±5.9 | 1.6±1.8 | 1.2±2.3 | 6.21±1.81 | 2.62±0.56 | 1.29±0.39 | ||||||
| Kamińska et al. (9) | Poland | 2018 | STEMI/NSTEMI/UA | 33/30/30 | STEMI | NSTEMI | UA | STEMI | NSTEMI | UA | ||
| hs-CRP (mg/L) | 3.5 (1.4-5.0) | 2.0 (0.9-3.9) | 1.3 (0.9-2.9) | 12.8 (9.9-17.4) | 18.8 (12.2-24.1) | 5.4 (2.2-11.0) | ||||||
| Wang et al. (6) | China | 2014 | AMI/UA | 33/27 | AMI | UA | AMI | UA | ||||
| hs-CRP (mg/L) | 8.91±2.12 | 5.95±1.60 | 32.50±9.32 | 24.41±8.68 | ||||||||
AMI, acute myocardial infarction; IL-6, interleukin-6; STEMI, ST-elevation myocardial infarction; NSTEMI, non-ST-elevation myocardial infarction; ACS, acute coronary syndrome; UA, unstable angina; hs-CRP, high-sensitivity C-reactive protein. Data are shown as the mean±standard deviation; * versus control group, p<0.01; AMI includes STEMI and NSTEMI. Data regarding grouping, number of patients in each group, hs-CRP, standard deviation, and interquartile range of IL-6 were extracted from the included studies that mentioned the association between plasma IL-6 size and the severity of ACS.