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Characterization of AuNPs. Panel A. Transmission electron micrograph of uncoated 5 nm particles. The average primary size was 5 ± 2 nm (mean ± SD) based upon measurement of 100 particles. Panel B. Particle size distribution of 5 nm AuNPs. Particle size distributions for 1 kDa, 2 kDa and 5 kDa PEG-coated particles. The average hydrodynamic radiuses were 12 ± 2, 16 ± 2 and 22 ± 4, respectively (mean ± SD).
