Table 1. Main pharmacokinetic parameters (mean ± SD, n = 4) of IVM after subcutaneous administration of SD1:3 and IVM in rabbits.
Parameters | IVM | SD1:3 |
---|---|---|
Cmax(ng/mL) | 22.25 ± 5.97 | 18.18 ± 8.53 |
Tmax (day) | 1.50 ± 0.58 | 2.75 ± 2.87 |
AUCINF (ng day/mL) | 255.61 ± 68.63 | 277.6 ± 84.91 |
MRT (day) | 18.45 ± 4.97 | 30.31 ± 5.61a |
The letter “a” denotes significant differences between the SD1:3 and the IVM group (p < 0.05).