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. 2017 Mar 10;24(1):622–631. doi: 10.1080/10717544.2017.1284945

Table 1. Main pharmacokinetic parameters (mean ± SD, n = 4) of IVM after subcutaneous administration of SD1:3 and IVM in rabbits.

Parameters IVM SD1:3
Cmax(ng/mL) 22.25 ± 5.97 18.18 ± 8.53
Tmax (day) 1.50 ± 0.58 2.75 ± 2.87
AUCINF (ng day/mL) 255.61 ± 68.63 277.6 ± 84.91
MRT (day) 18.45 ± 4.97 30.31 ± 5.61a

The letter “a” denotes significant differences between the SD1:3 and the IVM group (p < 0.05).