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. 2017 Apr 24;24(1):720–728. doi: 10.1080/10717544.2017.1311968

Table 2. Pharmacokinetic parameters of baicalin in rats after oral administration of baicalein, BaPC and BaPC-MD (n = 6).

Pharmacokinetic parameters Baicalein BaPC BaPC-MD
Cmax (μg/mL) 1.61 ± 0.37 8.68 ± 1.35* 12.75 ± 1.77* #
Tmax (min) 170.00 ± 65.73 33.33 ± 8.67* 48.33 ± 8.22*
AUC0–t (μg/mL min) 664.68 ± 73.50 1748.20 ± 280.80* 3331.04 ± 773.37* #
AUC0–∞(μg/mL min) 720.56 ± 283.77 2227.61 ± 753.50* 6218.58 ± 1561.37* #

Data were expressed as means ± SD.

*

p < 0.05 versus baicalein.

#

p < 0.05 versus BaPC.