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. 2017 May 16;24(1):811–817. doi: 10.1080/10717544.2017.1324530

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© 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/Licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Levels of the inflammatory cytokines in the colon tissue of colitis mice after treatment with LMWH, blank NP and LMWH-NP. Data are shown as mean ± S.D (n = 5). *, $= p < 0.05 compared to each of the colitis control and LMWH groups respectively. Only LMWH-NP (500 IU/kg) were able to achieve an efficient and significant reduction of TNF-α IL-1β in comparison with colitis control, while LMWH (100 IU/kg) showed no significant efficiency. Both the blank and drug-loaded NP have significantly reduced the levels of IL-6.