Table 2. Log(Kp) and IC50 values of sunitinib and SER–SUT conjugate.
| IC50 (μM) |
|||
|---|---|---|---|
| Compound | Log(Kp) | MCF-7 | MCF-10A |
| Sunitinib | 3.4 ± 0.2 | 24.6 ± 1.2 | >76 |
| Sericin–sunitinib conjugate | 4.1 ± 0.3 | 7.8 ± 0.9 | >76 |
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