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. 2017 Jul 4;24(1):1018–1025. doi: 10.1080/10717544.2017.1344335

Table 1.

Pharmacokinetic parameters.

Parameter AUC (h·ng/mL) Cmax (ng/mL) Tmax (h)
Drug 8.39 ± 4.78 4.70 ± 4.46 0.60 ± 1.02
Commercial soft capsule 8.79 ± 5.32 4.25 ± 2.63 0.62 ± 1.01
S-SNEDDS 28.25 ± 24.25* 10.65 ± 10.41* 1.05 ± 0.69*

Each value represents the mean ± SD (n = 8).

The S-SNEDDS was composed of PLAG/SLS/HPMC/BHA/calcium silicate at a weight ratio of 1: 0.25: 0.1: 0.0002: 0.5.

*

p < .05 compared with drug and commercial soft capsule.