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Distribution of FITC-PLL solution topically applied with or without RED on porcine skin. All images in this figure are magnified at 200×. Control, no treatment; passive diffusion, only topical application for 30 min and 1 h, respectively; RED, iontophoretic drug delivery for 30 min and 1 h, respectively (Left column, differential interference contrast (DIC) images; middle column, fluorescence images; right column, merged images).
