Table 3.

Summary of the pharmacokinetic parameters of MSP following the sublingual administration of Fluxopride^® and the optimized test formulation.

Parameters	Fluxopride®	T2
Cmax (ng/ml)	31.31 ± 9.65	42.38 ± 11.33
Tmax (median) (h)	1.125	1.125
MRT (median) (h)	4.70	5.66
AUC0–10 (ng h/ml)	103.25 ± 28.28	136.06 ± 41.43
AUC 0–∞ (ng h/ml)*	117.41 ± 26.70	165.99 ± 50.02
t1/2 (h)	3.34 ± 1.28	3.85 ± 0.79
k (h−1)	0.22 ± 0.06	0.18 ± 0.03

^*p < 0.05 (0.03).