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. 2017 Jun 29;24(1):1011–1017. doi: 10.1080/10717544.2017.1344336

Table 1.

Pharmacokinetic parameters based on noncompartmental pharmacokinetic analyses for embolization with CBDOX or cTACE of doxorubicin solution to rabbit livers (n = 5).

Parameters Units TACE with CBDOX cTACE
C max ng/mL 39.85 ± 13.86 225.91 ± 64.88#
AUC(0–t) mg/L*h 191.18 ± 40.36 275.94 ± 27.45#
MRT(0–t) h 157.78 ± 130.86 26.58 ± 12.45
T 1/2 h 109.84 ± 90.88 23.17 ± 10.43

Cmax: maximum plasma concentration; AUC: area under the curve; T1/2: half-time; MRT: mean residence time.

#

p<.01.