Table 1.

The sol–gel transition temperature of agomelatine loaded SLNs in situ gels prepared using 18% w/v of Pluronic F 127 and 0.2% w/v of different types of mucoadhesive polymers.

Mucoadhesive polymer	Sol–gel transition temperatures (°C)
Carbopol	22.25 ± 1.06
Chitosan	20.50 ± 0.71
Na alginate	31.50 ± 2.12
Na CMC	22.50 ± 2.12
HPMC	29.00 ± 1.41