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. 2017 Feb 6;24(1):328–338. doi: 10.1080/10717544.2016.1250140

Table 1. Composition and pre-compression characterization of risperidone liquisolid formulae.

Formula Vehicle type LDCa Lf Q q Disb Unit dose weight (mg) Angle of repose Ci% Hausner ratio
F1 Transcutol HP 10 0.243 165 8.25 17.325 192.48 32.22 17.84 1.21
F2   20   83 4.15 8.715 96.82 31.16 19.16 1.19
F3   30   55 2.75 5.775 64.16 31.62 18.18 1.18
F4 Labrasol 10 0.202 198 9.9 20.76 230.64 30.12 17.67 1.17
F5   20   99 4.95 10.395 115.49 29.86 16.16 1.19
F6   30   66 3.3 6.93 76.994 30.25 16.87 1.16
F7 PEG 400 10 0.104 385 19.25 40.425 449.12 31.12 20.01 1.12
F8   20   193 9.65 20.265 225.14 31.24 18.79 1.14
F9   30   128 6.4 13.44 149.32 32.11 18.89 1.17
F10 Tween 80 10 0.142 282 14.1 29.61 328.97 30.35 18.13 1.20
F11   20   141 7.05 14.805 164.43 31.63 18.87 1.18
F12   30   94 4.7 9.87 109.66 32.15 17.82 1.19
F13 Labrasol/Labrafil (1:1) 10 0.151 265 13.25 27.825 309.14 30.75 18.92 1.17
F14   20   133 6.65 13.965 155.15 31.41 19.37 1.17
F15   30   89 4.45 9.345 103.82 31.82 19.41 1.16

aLiquid drug concentration.

b

Disintegrant amount (mg).