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. 2017 Nov 28;24(1):1843–1855. doi: 10.1080/10717544.2017.1386731

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© 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Characterization of glycolipid-like copolymer micelles. (A) ¹HNMR spectra of CSO, PEG₂₀₀₀, Ap, CSSA and Ap-CSSA in D₂O. (B) TEM images of blank vehicles and DOX-loaded nanoparticles (Scale bar =50 nm). (C) The pyrene fluorescence intensity ratio of I₁/I₃ as a function of the logarithmic concentration (−Log C) of CSSA and Ap-CSSA copolymer micelles. (D) In vitro DOX release behaviors of CSSA/DOX and Ap-CSSA/DOX nanoparticles in PBS of pH 7.4 and pH 6.5 (n = 3). (E) DOX, CSSA/DOX nanoparticles and Ap-CSSA/DOX nanoparticles against U87 MG with a concentration of 0–10 μg DOX-equiv./mL for 48 h. (n = 5).